Spicy Southern Cheesy Chicken Spaghetti Casserole

Ingredients

- 6 +

• 8 oz spaghetti
• 2 cups cooked chicken, shredded
• 1 can (10 oz) diced tomatoes with green chilies
• 1 cup cream cheese, softened
• 1 cup shredded cheddar cheese
• 1/2 cup milk
• 1/2 teaspoon garlic powder
• 1/2 teaspoon onion powder
• 1 teaspoon paprika
• Salt and pepper to taste
• 1/4 cup chopped green onions (for garnish)

Instructions

1

Preheat oven to 350°F (175°C).

Done!

2

Cook spaghetti according to package instructions until al dente, drain and set aside.

Done!

3

In a large bowl, combine shredded chicken, diced tomatoes, cream cheese, milk, garlic powder, onion powder, paprika, salt, and pepper.

Done!

4

Add cooked spaghetti to the chicken mixture and stir until well combined.

Done!

5

Transfer the mixture to a greased 9x13 inch baking dish and spread evenly.

Done!

6

Sprinkle cheddar cheese on top.

Done!

7

Bake for 30-35 minutes or until the casserole is bubbly and golden brown.

Done!

8

Remove from oven and let sit for 5 minutes before serving. Garnish with chopped green onions.

Done!

Kitchen Tools

• Large pot for boiling spaghetti
• Mixing bowl
• 9x13 inch baking dish
• Spatula for mixing

Chef's Tips

For additional heat, add chopped jalapeños to the mixture.

Feel free to substitute the chicken with turkey or rotisserie chicken for convenience.

Troubleshooting

If the casserole is too dry, add a splash more milk before baking.

If the top is browning too quickly, cover it loosely with foil during baking.

Recipe Variations

Add bell peppers and corn for extra veggies.

Use different cheese varieties such as pepper jack for a spicier kick.

Healthy Alternatives

Use whole wheat spaghetti for a healthier option.

Replace cream cheese with Greek yogurt for reduced fat.

Serving Suggestions

Serve with a side salad for a complete meal.

Pair with garlic bread for an extra cheesy experience.

Nutrition Facts

425

Calories

28g

Protein

42g

Carbs

16g

Fat

2g

Fiber

3g

Sugar

890mg

Sodium

75mg

Cholesterol

Dietary Info

Can be made gluten-free

Dairy-free option available with substitutions

Garnish Ideas

Chopped fresh cilantro for a burst of flavor.

Sour cream on top for added creaminess.

Storage

Store leftovers in an airtight container in the refrigerator for up to 3 days.

You can freeze the assembled casserole before baking for up to 2 months.

Leftover Ideas

Reheat in the microwave for a quick lunch.

Transform leftovers into a wrap using tortillas.

Common Mistakes to Avoid

Overcooking the spaghetti can make it mushy once baked.

Not allowing the casserole to rest can make it fall apart when serving.

Frequently Asked Questions

Can I make this casserole ahead of time?

Yes! You can assemble the casserole and refrigerate it for up to 24 hours before baking.

What can I substitute for chicken?

You can use turkey, beef, or even keep it vegetarian by adding beans.

How spicy is this casserole?

It has a mild spice from the tomatoes and can be adjusted to your preference by adding more peppers.

Can I make this recipe dairy-free?

Yes! Use dairy-free cheese and cream cheese alternatives.

What if I don't have spaghetti?

You can substitute with any pasta you have on hand, like penne or fusilli.

How should I store leftovers?

Store in an airtight container in the fridge for up to 3 days.

What's a good side dish to serve with this casserole?

A simple green salad or steamed vegetables go well as side dishes.

Reviews

Sarah M

Mar 3, 2026

Absolutely loved this recipe! It was a hit at dinner.

John D

Mar 20, 2026

Really tasty, but I think it could use a bit more spice!

Emily T

Mar 15, 2026

The whole family enjoyed it! Super creamy and cheesy.

Brian L

Mar 2, 2026

Great comfort food, however, took a bit longer to bake.

Karen S

Mar 22, 2026

This is a new staple in my house. So easy to make!

Katie W

Mar 19, 2026

Delicious, mouthwatering casserole! I’ll definitely make it again.

Michael Z

Feb 28, 2026

It was good, but felt a bit too rich for my taste.

Laura P

Feb 25, 2026

Easy to prepare and very filling. I'll be adding more veggies next time.

Raj K

Mar 15, 2026

This casserole was a real crowd-pleaser at my party!

Angela F

Feb 28, 2026

So cheesy! My kids couldn't get enough.

Tom H

Mar 15, 2026

Flavorful and comforting, but a bit too much sodium for my preference.

Nina R

Mar 10, 2026

A delicious twist on a classic, I am in love!

Gina M

Mar 9, 2026

Solid recipe! Perfect for potlucks.

Dan B

Feb 23, 2026

Tasty and satisfying, but I wish it had more kick.

Lucy A

Mar 8, 2026

A new favorite! I can't wait to share it with friends.